C22 Glucosylceramide (d18:1/22:0)

C22 Glucosylceramide is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide (Cay-16983), as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice fed a methionine-restricted diet. In human athletes, plasma levels of C22 glucosylceramide increase during exercise and return to basal levels during recovery. This product contains C22 glucosylceramide isolated from bovine buttermilk. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1531]Formal Name: N-[(1S,2R,3E)-1-[(beta-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-docosanamide. CAS Number: 119242-44-3. Synonyms: N-C22:0-Glucocerebroside, C22 Glucosylceramide, GluCer(18:1/22:0), Glucosylceramide (d18:1/22:0, N-Docosanoyl-beta-glucosylsphingosine, N-Docosanoyl-glucopsychosine. Molecular Formula: C46H89NO8. Formula Weight: 784.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble. SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@@H]1O. InChi Code: InChI=1S/C46H89NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-42(50)47-39(38-54-46-45(53)44(52)43(51)41(37-48)55-46)40(49)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,39-41,43-46,48-49,51-53H,3-32,34,36-38H2,1-2H3,(H,47,50)/b35-33+/t39-,40+,41+,43+,44-,45+,46+/m0/s1. InChi Key: YIGARKIIFOHVPF-CNUVFPMCSA-N.