Aspirin

Aspirin
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay70260-50 50 g -

6 - 10 Werktage*

20,00 €
Cay70260-100 100 g -

6 - 10 Werktage*

27,00 €
Cay70260-500 500 g -

6 - 10 Werktage*

77,00 €
 
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) and a covalent inhibitor of COX-1 and... mehr
Produktinformationen "Aspirin"
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) and a covalent inhibitor of COX-1 and COX-2 (IC50s = 4.45 and 13.88 µM, respectively, for the human enzymes). It is also an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 750 µM for the ovine enzyme). Aspirin (6 µg/ml) inhibits epinephrine- and ADP-induced platelet aggregation. In vivo, aspirin (30 mg/kg) reduces infarct volume and microglial infiltration in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO). It decreases macrophage infiltration into, increases the number of smooth muscle cells and levels of collagen in, and reduces the area of, atherosclerotic lesions in LDL receptor-deficient mice fed a high-fat diet when administered in the drinking water at 30 mg/L. Formulations containing aspirin have been used in the treatment of pain, fever, and in stroke prevention.Formal Name: 2-(acetyloxy)-benzoic acid. CAS Number: 50-78-2. Synonyms: Acetylsalicylic Acid, NSC 27223, NSC 406186. Molecular Formula: C9H8O4. Formula Weight: 180.2. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: >30 mg/ml, DMSO: >41 mg/ml, Ethanol: >80 mg/ml, PBS pH 7.2: >2.7 mg/ml. lambdamax: 226, 275 nm. SMILES: CC(=O)Oc1ccccc1C(=O)O. InChi Code: InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12). InChi Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N. Origin: Synthetic.
Schlagworte: Acetylsalicylic Acid, NSC 27223, NSC 406186, 2-(acetyloxy)-benzoic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 70260

Eigenschaften

Anwendung: COX inhibitor
MW: 180.2 D
Formel: C9H8O4
Reinheit: >90%
Format: Crystalline Solid

Datenbank Information

CAS : 50-78-2| Passende Produkte
KEGG ID : K11987 | Passende Produkte

Handhabung & Sicherheit

Lagerung: +20°C
Versand: +20°C (International: +20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302, H315, H319, H335
P-Sätze: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Aspirin"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen