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Artikelnummer: Cay50651-50
(±)14(15)-EET is a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) that is formed via epoxidation of arachidonic acid by cytochrome P450. It prevents increases in leukotriene B4 (LTB4, Cay-20110), ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) induced by oxidized LDL in primary rat pulmonary...
Schlagworte: | (±)14,15-EET, (±)14,15-EpETrE, (±)14(15)-epoxy-5Z,8Z,11Z-eicosatrienoic acid |
Anwendung: | Bioactive lipid assays |
CAS | 197508-62-6 |
MW: | 320.5 D |
ab 66,00 €
Artikelnummer: Cay90010-100
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
Schlagworte: | AA, 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Anwendung: | Bioactive lipid assays |
CAS | 506-32-1 |
MW: | 304.5 D |
ab 39,00 €
Artikelnummer: Cay16010-10
Prostaglandin F2alpha (PGF2alpha) is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. PGF2alpha exerts its receptor mediated physiological activity at 50-100 nM. Maximal ovine...
Schlagworte: | Dinoprost, PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Anwendung: | Bioactive lipid assays |
CAS | 551-11-1 |
MW: | 354.5 D |
ab 50,00 €
Artikelnummer: Cay38400-100
(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs...
Schlagworte: | (±)-9-hydroxy-10E,12Z-octadecadienoic acid |
Anwendung: | Bioactive lipid studies |
CAS | 98524-19-7 |
MW: | 296.5 D |
ab 193,00 €
Artikelnummer: Cay10012554-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced...
Schlagworte: | 17(S)-Resolvin D1, RvD1, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid |
Anwendung: | Bioactive lipid assays |
CAS | 872993-05-0 |
MW: | 376.5 D |
ab 205,00 €
Artikelnummer: Cay18570-1
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
Schlagworte: | 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid |
Anwendung: | Bioactive lipid assays |
CAS | 87893-55-8 |
MW: | 316.4 D |
ab 43,00 €
Artikelnummer: Cay16350-1
8-iso PGF2alpha is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2alpha...
Schlagworte: | 15-F2t-Isoprostane, 8-epi PGF2alpha, 8-iso-15(S)-Prostaglandin F2alpha, 8-Isoprostane, iPF2alpha-III,... |
Anwendung: | TP receptor agonist |
CAS | 27415-26-5 |
MW: | 354.5 D |
ab 220,00 €
Artikelnummer: Cay90110-50
EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some...
Schlagworte: | EPA, Timnodonic Acid, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
Anwendung: | Bioactive lipid assays |
CAS | 10417-94-4 |
MW: | 302.5 D |
ab 50,00 €
Artikelnummer: Cay390010-1
Arachidonic acid-d8 is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane...
Schlagworte: | AA-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
Anwendung: | Standard |
CAS | 69254-37-1 |
MW: | 312.5 D |
ab 164,00 €
Artikelnummer: Cay90410-25
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE (Cay-34700) or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 (Cay-20110) in inducing superoxide generation in human neutrophils at 0.1 µM. LXA4 is associated with several...
Schlagworte: | 5(S),6(R),15(S)-TriHETE, LXA4, 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid |
Anwendung: | Bioactive lipid assays |
CAS | 89663-86-5 |
MW: | 352.5 D |
ab 270,00 €
Artikelnummer: Cay90050-5
Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid, originally isolated from porcine brain. AEA is an endogenous cannabinoid neurotransmitter that binds to both cannabinoid 1 (CB1) and CB2 receptors. AEA has Ki values ranging from 61 to 543 nM for CB1 receptors and from 279 to 1,940 nM for...
Schlagworte: | AEA, Anandamide, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Anwendung: | Bioactive Lipid assays |
CAS | 94421-68-8 |
MW: | 347.5 D |
ab 54,00 €
Artikelnummer: Cay62580-1
Fumonisin B1 (FB1) is a mycotoxin that has been found in F. moniliforme. It inhibits ceramide synthase (IC50 = 0.1 µM for the rat liver enzyme). FB1 induces DNA fragmentation and apoptosis in CV-1 cells when used at concentrations of 5 and 25 µM, respectively. It is cytotoxic to primary rat hepatocytes and induces...
Schlagworte: | FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,... |
Anwendung: | Ceramide synthase inhibitor |
CAS | 116355-83-0 |
MW: | 721.8 D |
ab 98,00 €