Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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Prostaglandin F2alpha
Prostaglandin F2alpha

Artikelnummer: Cay16010-5

Prostaglandin F2alpha (PGF2alpha) is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. PGF2alpha exerts its receptor mediated physiological activity at 50-100 nM. Maximal ovine...
Schlagworte: Dinoprost, PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 551-11-1
MW: 354.5 D
ab 37,00 €
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(±)9-HODE
(±)9-HODE

Artikelnummer: Cay38400-100

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs...
Schlagworte: (±)-9-hydroxy-10E,12Z-octadecadienoic acid
Anwendung: Bioactive lipid studies
CAS 98524-19-7
MW: 296.5 D
ab 157,00 €
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15-keto Prostaglandin E1
15-keto Prostaglandin E1

Artikelnummer: Cay13680-1

15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1. Formal Name: 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid. CAS Number: 22973-19-9. Synonyms: 15-keto PGE1. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity:...
Schlagworte: 15-keto PGE1, 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid
Anwendung: Bioactive lipid assays
CAS 22973-19-9
MW: 352.5 D
ab 65,00 €
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15-deoxy-Delta12,14-Prostaglandin J2
15-deoxy-Delta12,14-Prostaglandin J2

Artikelnummer: Cay18570-1

15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
Schlagworte: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Anwendung: Bioactive lipid assays
CAS 87893-55-8
MW: 316.4 D
ab 32,00 €
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Resolvin D1
Resolvin D1

Artikelnummer: Cay10012554-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced...
Schlagworte: 17(S)-Resolvin D1, RvD1, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid
Anwendung: Bioactive lipid assays
CAS 872993-05-0
MW: 376.5 D
ab 157,00 €
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8-iso Prostaglandin F2alpha
8-iso Prostaglandin F2alpha

Artikelnummer: Cay16350-1

8-iso PGF2alpha is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2alpha...
Schlagworte: 15-F2t-Isoprostane, 8-epi PGF2alpha, 8-iso-15(S)-Prostaglandin F2alpha, 8-Isoprostane, iPF2alpha-III,...
Anwendung: TP receptor agonist
CAS 27415-26-5
MW: 354.5 D
ab 157,00 €
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Prostaglandin I2 (sodium salt)
Prostaglandin I2 (sodium salt)

Artikelnummer: Cay18220-1

Prostaglandin I2 (PGI2) is an unstable cyclooxygenase metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 of 5 nM. PGI2 is stable in basic buffers (pH=8), but it is rapidly hydrolyzed to 6-keto...
Schlagworte: Epoprostenol, PGI2, Prostacyclin, 6,9alpha-epoxy-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, monosodium salt
Anwendung: Bioactive lipid assays
CAS 61849-14-7
MW: 374.5 D
ab 74,00 €
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N-3-oxo-dodecanoyl-L-Homoserine lactone
N-3-oxo-dodecanoyl-L-Homoserine lactone

Artikelnummer: Cay10007895-1

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators...
Schlagworte: 3-oxo-C12-HSL, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-dodecanamide
Anwendung: Bioactive lipid assays
CAS 168982-69-2
MW: 297.4 D
ab 29,00 €
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Eicosapentaenoic Acid
Eicosapentaenoic Acid

Artikelnummer: Cay90110-50

EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some...
Schlagworte: EPA, Timnodonic Acid, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid
Anwendung: Bioactive lipid assays
CAS 10417-94-4
MW: 302.5 D
ab 37,00 €
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Lipoxin A4
Lipoxin A4

Artikelnummer: Cay90410-25

Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE (Cay-34700) or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 (Cay-20110) in inducing superoxide generation in human neutrophils at 0.1 µM. LXA4 is associated with several...
Schlagworte: 5(S),6(R),15(S)-TriHETE, LXA4, 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 89663-86-5
MW: 352.5 D
ab 207,00 €
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Resolvin D2
Resolvin D2

Artikelnummer: Cay10007279-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
Schlagworte: 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid
Anwendung: Lipid mediator
CAS 810668-37-2
MW: 376.5 D
ab 157,00 €
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Fumonisin B1
Fumonisin B1

Artikelnummer: Cay62580-1

Fumonisin B1 is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)....
Schlagworte: FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,...
Anwendung: Ceramide synthase inhibitor
CAS 116355-83-0
MW: 721.8 D
ab 74,00 €
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