9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2, Cay-14010) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1alpha is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1alpha, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.Formal Name: 11alpha,15R-dihydroxy-16,16-dimethyl-9-methylene-prosta-5Z,13E-dien-1-oic acid. CAS Number: 61263-35-2. Synonyms: Meteneprost, 9-deoxy-9-methylene-16,16-dimethyl PGE2. Molecular Formula: C23H38O4. Formula Weight: 378.6. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): >5 mg/ml. SMILES: CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)C(C[C@H]1O)=C. InChi Code: InChI=1S/C23H38O4/c1-5-6-15-23(3,4)21(25)14-13-19-18(17(2)16-20(19)24)11-9-7-8-10-12-22(26)27/h7,9,13-14,18-21,24-25H,2,5-6,8,10-12,15-16H2,1,3-4H3,(H,26,27)/b9-7-,14-13+/t18-,19+,20+,21+/m0/s1. InChi Key: WMLGLMGSFIXSGO-KTXJXPLISA-N.