8-iso Prostaglandin E2 isopropyl ester

8-iso Prostaglandin E2 isopropyl ester (8-iso PGE2 isopropyl ester) is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.Formal Name: (8beta)-11,15S-dihydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid, 1-methylethyl ester. CAS Number: 330589-21-4. Synonyms: 8-iso PGE2 isopropyl ester. Molecular Formula: C23H38O5. Formula Weight: 394.6. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >30 mg/ml, DMSO: >50 mg/ml, Ethanol: >50 mg/ml, PBS (pH 7.2): <50 µg/ml. SMILES: O=C1[C@@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C23H38O5/c1-4-5-8-11-18(24)14-15-20-19(21(25)16-22(20)26)12-9-6-7-10-13-23(27)28-17(2)3/h6,9,14-15,17-20,22,24,26H,4-5,7-8,10-13,16H2,1-3H3/b9-6-,15-14+/t18-,19-,20+,22+/m0/s1. InChi Key: NOHLKSJQMSPOTB-YRLDPNHWSA-N.