8-iso-17-phenyl trinor Prostaglandin F2beta

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay10008436-100	100 µg	-	5 - 10 Werktage*	57,00 €
Cay10008436-500	500 µg	-	5 - 10 Werktage*	212,00 €
Cay10008436-1	1 mg	-	5 - 10 Werktage*	372,00 €

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Bimatoprost (free acid) is a metabolically stable analog of prostaglandin F2alpha (PGF2alpha) and... mehr

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Produktinformationen "8-iso-17-phenyl trinor Prostaglandin F2beta"

Bimatoprost (free acid) is a metabolically stable analog of prostaglandin F2alpha (PGF2alpha) and a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. At the rat recombinant FP receptor expressed in CHO cells bimatoprost inhibits PGF2alpha binding with a Ki of 1.1 nM. The isopropyl ester of bimatoprost is slightly better than PGF2alpha isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation. 8-iso-17-phenyl PGF2beta is an isomer of bimatoprost that is epimerized at the 8 and 9 positions. There are no published reports on the biological activity of 8-iso-17-phenyl PGF2beta.

Schlagworte:	9beta,11alpha,15S-trihydroxy-17-phenyl-(8beta)-prosta-5Z,13E-dien-1-oic acid
Hersteller:	Cayman Chemical
Hersteller-Nr:	10008436

Eigenschaften

Anwendung:	FP receptor agonist
MW:	388.5 D
Formel:	C23H32O5
Reinheit:	>98%
Format:	Solution

Datenbank Information

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H225, H319, H336, EUH066
P-Sätze:	P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501