(±)5(6)-EpETE methyl ester

(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.(±) 5(6)-EpETE methyl ester is a chemically less reactive derivative of 5(6)-EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in subjects on a typical western diet these compounds are generally not detected. The specific biologic activity of 5(6)-EpETE and its methyl ester have not been documented.Formal Name: (±)5(6)-epoxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid, methyl ester. CAS Number: 127716-49-8. Synonyms: (±)5,6-EEQ methyl ester, (±)5,6-epoxy Eicosatetraenoic Acid methyl ester. Molecular Formula: C21H32O3. Formula Weight: 332.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 10 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:1): 500 µg/ml. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C[C@H]1O[C@H]1CCCC(=O)OC. InChi Code: InChI=1S/C21H32O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h4-5,7-8,10-11,13-14,19-20H,3,6,9,12,15-18H2,1-2H3/b5-4-,8-7-,11-10-,14-13-/t19-,20+/m1/s1. InChi Key: BDSCYYACNUKQLZ-AECQIINDSA-N.