20-carboxy Arachidonic Acid

20-carboxy Arachidonic Acid
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007912-25 25 µg -

6 - 10 Werktage*

300,00 €
Cay10007912-50 50 µg -

6 - 10 Werktage*

568,00 €
Cay10007912-100 100 µg -

6 - 10 Werktage*

1.071,00 €
 
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in... mehr
Produktinformationen "20-carboxy Arachidonic Acid"
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This omega-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B. Like 20-HETE, 20-COOH-AA inhibits ion transport in the kidneys. It also produces vasorelaxation of porcine coronary microvessels constricted with endothelin. 20-COOH-AA binds to isolated ligand binding domains of peroxisome proliferator-activated receptor alpha (PPARalpha) (Kd = 0.87 ± 0.12 µM) and PPARgamma (Kd = 1.7 ± 0.5 µM), and is a dual activator of PPARalpha and PPARgamma in a transiently transfected COS-7 cell reporter system.Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenedioic acid. CAS Number: 79551-84-1. Synonyms: 20-carboxy AA, 20-COOH-AA. Molecular Formula: C20H30O4. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.1 M Na2CO3: 1.5 mg/ml, DMF: 100 mg/ml, DMSO: 100 mg/ml, Ethanol: 100 mg/ml. SMILES: OC(=O)CCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H30O4/c21-19(22)17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(23)24/h1,3-4,6-7,9-10,12H,2,5,8,11,13-18H2,(H,21,22)(H,23,24)/b3-1-,6-4-,9-7-,12-10-. InChi Key: BGOJKUCHTMYINI-DTLRTWKJSA-N.
Schlagworte: 20-carboxy AA, 20-COOH-AA, 5Z,8Z,11Z,14Z-eicosatetraenedioic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 10007912

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 334.5 D
Formel: C20H30O4
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 79551-84-1| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H319
P-Sätze: P210, P233, P240, P241, P242, P243, P264, P280, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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