17-trifluoromethylphenyl trinor Prostaglandin F2alpha

17-trifluoromethylphenyl trinor Prostaglandin F2alpha
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay16890-1 1 mg -

5 - 10 Werktage*

62,00 €
Cay16890-5 5 mg -

5 - 10 Werktage*

277,00 €
Cay16890-10 10 mg -

5 - 10 Werktage*

490,00 €
 
A number of 17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have... mehr
Produktinformationen "17-trifluoromethylphenyl trinor Prostaglandin F2alpha"
A number of 17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2alpha bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2alpha would act very much like the free acid of travoprost. 17-phenyl trinor PGF2alpha is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol. Formal Name: 9alpha,11alpha,15S-trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid. CAS Number: 221246-34-0. Synonyms: 17-trifluoromethylphenyl trinor PGF2alpha. Molecular Formula: C24H31O5F3. Formula Weight: 456.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC(C(F)(F)F)=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1. InChi Key: CMLNDCUXASGBMQ-NQUQXYBYSA-N.
Schlagworte: 17-trifluoromethylphenyl trinor PGF2alpha, 9alpha,11alpha,15S-trihydroxy-17-trifluoromethylphenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 16890

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 456.5 D
Formel: C24H31O5F3
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 221246-34-0| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: EUH066, H225, H319, H336
P-Sätze: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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