13,14-dihydro-15-keto Prostaglandin D2-d4

13,14-dihydro-15-keto Prostaglandin D2-d4
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007978-25 25 µg -

5 - 10 Werktage*

144,00 €
Cay10007978-50 50 µg -

5 - 10 Werktage*

274,00 €
Cay10007978-100 100 µg -

5 - 10 Werktage*

518,00 €
 
13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) contains four deuterium... mehr
Produktinformationen "13,14-dihydro-15-keto Prostaglandin D2-d4"
13,14-dihydro-15-keto Prostaglandin D2-d4 (13,14-dihydro-15-keto PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGD2 is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor. It also inhibits ion flux in a canine colonic mucosa preparation. In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11beta-hydroxy compounds which have also undergone beta-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine. Formal Name: 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-3,3,4,4-d4 acid. Synonyms: 13,14-dihydro-15-keto PGD2-d4. Molecular Formula: C20H28D4O5. Formula Weight: 356.5. Purity: >99% deuterated forms (d1-d4). Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 30 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 2 mg/ml. SMILES: O[C@@H](C1)[C@H](C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)[C@@H](CCC(CCCCC)=O)C1=O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-18,22H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+/m1/s1/i5D2,8D2. InChi Key: VSRXYLYXIXYEST-URWDITFUSA-N.
Schlagworte: 13,14-dihydro-15-keto PGD2-d4, 9alpha-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-3,3,4,4-d4 acid
Hersteller: Cayman Chemical
Hersteller-Nr: 10007978

Eigenschaften

Anwendung: Standard
MW: 356.5 D
Formel: C20H28D4O5
Reinheit: >99% deuterated forms (d1-d4)
Format: Solution

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H302, H316, H319, H336, H360
P-Sätze: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+310, P303+361+353, P304+340, P305+351+338, P308+313, P312, P330, P332+313, P337+313, P370+378, P403+233, P403+235, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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