11-deoxy-11-methylene Prostaglandin D2

11-deoxy-11-methylene Prostaglandin D2
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay12410-1 1 mg -

5 - 10 Werktage*

72,00 €
Cay12410-5 5 mg -

5 - 10 Werktage*

322,00 €
Cay12410-10 10 mg -

5 - 10 Werktage*

570,00 €
 
Prostaglandin D2 (PGD2, Cay-12010) is one of the five primary enzymatic prostaglandins derived... mehr
Produktinformationen "11-deoxy-11-methylene Prostaglandin D2"
Prostaglandin D2 (PGD2, Cay-12010) is one of the five primary enzymatic prostaglandins derived directly from PGH2 (Cay-17020). PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin. However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay. The CRTH2-receptor actions of 11-deoxy-11-methylene PGD2 are not yet reported.
Schlagworte: 11-deoxy-11-methylene PGD2, 9alpha,15S-dihydroxy-11-methylene-prosta-5Z,13E-dien-1-oic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 12410

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 350.5 D
Formel: C21H34O4
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 100648-29-1| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H319, H336, H360, EUH066
P-Sätze: P201, P202, P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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