1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Cay-10011298) and arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques. Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma. SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors. SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.Formal Name: 1-ocatadeconyl-2R-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glyceryl-3-phosphorylcholine. CAS Number: 35418-59-8. Synonyms: 18:0/20:4-PC, PC(18:0/20:4), SAPC, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine. Molecular Formula: C46H84NO8P. Formula Weight: 810.1. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/ml. SMILES: O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O. InChi Code: InChI=1S/C46H84NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h14,16,20,22,25,27,31,33,44H,6-13,15,17-19,21,23-24,26,28-30,32,34-43H. InChi Key: PSVRFUPOQYJOOZ-QNPWAGBNSA-N. Side Chain Carbon Sum: 38:4.