(±)-trans-GK563

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay25732-1	1 mg	-	6 - 10 Werktage*	125,00 €
Cay25732-5	5 mg	-	6 - 10 Werktage*	549,00 €
Cay25732-10	10 mg	-	6 - 10 Werktage*	966,00 €

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trans-(±)-GK563 is a potent beta-lactone inhibitor of group VIA (GVIA) calcium-independent... mehr

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Produktinformationen "(±)-trans-GK563"

trans-(±)-GK563 is a potent beta-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2, IC50 = 1 nM). It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 µM). trans-(±)-GK563 (1 and 10 µM) inhibits apoptosis induced by IL-1beta and IFN-gamma in INS-1 beta-cells.Formal Name: (3R,4R)-rel-3-(4-phenylbutyl)-4-propyl-2-oxetanone. CAS Number: 2351820-19-2. Synonyms: GK563. Molecular Formula: C16H22O2. Formula Weight: 246.3. Purity: >94%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: Chloroform: slightly soluble, DMSO: slightly soluble, Methanol: slightly soluble. SMILES: O=C1[C@@H](CCCCC2=CC=CC=C2)[C@H](CCC)O1. InChi Code: InChI=1S/C16H22O2/c1-2-8-15-14(16(17)18-15)12-7-6-11-13-9-4-3-5-10-13/h3-5,9-10,14-15H,2,6-8,11-12H2,1H3/t14-,15-/m0/s1. InChi Key: IAYKBJFWLAKGMR-GJZGRUSLSA-N.

Schlagworte:	GK563, (3R,4R)-rel-3-(4-phenylbutyl)-4-propyl-2-oxetanone
Hersteller:	Cayman Chemical
Hersteller-Nr:	25732

Eigenschaften

Anwendung:	iPLA2beta inhibitor
MW:	246.3 D
Formel:	C16H22O2
Reinheit:	>94%
Format:	Solution

Datenbank Information

CAS :	2351820-19-2\| Passende Produkte
KEGG ID :	K16343 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	-20°C (International: -20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H225, H319, H333, H336
P-Sätze:	P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+312, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501