Sulindac-d3

Sulindac-d3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay33381-500 500 µg -

6 - 10 Werktage*

163,00 €
Cay33381-1 1 mg -

6 - 10 Werktage*

308,00 €
Cay33381-5 5 mg -

6 - 10 Werktage*

1.287,00 €
 
Sulindac-d3 is intended for use as an internal standard for the quantification of sulindac... mehr
Produktinformationen "Sulindac-d3"
Sulindac-d3 is intended for use as an internal standard for the quantification of sulindac (Cay-10004386) by GC- or LC-MS. Sulindac is a non-steroidal anti-inflammatory drug (NSAID), selective COX-2 inhibitor (IC50s = 0.79 and >1,000 µM for COX-2 and COX-1, respectively), and prodrug form of sulindac sulfide (Cay-10004387). Sulindac is reduced by intestinal bacteria to form sulindac sulfide. It inhibits acetic acid-induced writhing in mice and reduces paw edema induced by carrageenan in rats when administered at a dose of 100 mg/kg. Sulindac (60 mg/kg) reduces tumor growth in MiaPaCa-2 and BxPC-3 mouse xenograft models. Formulations containing sulindac have been used in the treatment of pain associated with arthritis, ankylosing spondylitis, and gout.Formal Name: 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl-d3)phenyl]methylene]-1H-indene-3-acetic acid. Molecular Formula: C20H14D3FO3S. Formula Weight: 359.4. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble. SMILES: OC(CC1=C(C)/C(C2=CC=C(F)C=C21)=C/C3=CC=C(C=C3)S(C([2H])([2H])[2H])=O)=O. InChi Code: InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-/i2D3. InChi Key: MLKXDPUZXIRXEP-FHFLIJIYSA-N.
Schlagworte: 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl-d3)phenyl]methylene]-1H-indene-3-acetic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 33381

Eigenschaften

Anwendung: GC-MS, LC-MS, Internal standard, Quantification, COX inhibitor
MW: 359.4 D
Formel: C20H14D3FO3S
Reinheit: >99% deuterated forms (d1-d3)
Format: Solid

Datenbank Information

KEGG ID : K11987 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302, H312, H315, H319, H332
P-Sätze: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P361+364, P362+364, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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