SJ000291942

SJ000291942 is a bone morphogenic protein (BMP) signaling activator. It activates BMP4 in C33A-2D2 human cervical carcinoma clonal reporter cells (EC50 = =1 µM). SJ000291942 (0.1-50 µM) induces ventralization, as well as increases expression of the BMP target genes bmp2b and szl and the cooperatively-induced BMP target genes vent and vox in zebrafish embryos. It also induces BMP-dependent osteoblastic differentiation of C2C12 murine myoblasts.Formal Name: 2-(4-ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide. CAS Number: 425613-09-8. Molecular Formula: C16H15FN2O4. Formula Weight: 318.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml. lambdamax: 235 nm. SMILES: CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1. InChi Code: InChI=1S/C16H15FN2O4/c1-2-11-3-6-13(7-4-11)23-10-16(20)18-12-5-8-14(17)15(9-12)19(21)22/h3-9H,2,10H2,1H3,(H,18,20). InChi Key: YSZJLXPXVFGTNK-UHFFFAOYSA-N.