Okadaic Acid, Free Acid (Halochondrine A, CAS 78111-17-8), >98%

Solubility: Soluble in DMSO or ethanol. Special Hazard: TUMOR PROMOTER - Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure. Warnings: Highly irritant to skin and mucous membranes. Potent inhibitor of protein phosphatases, especially the PP-1 and PP-2 classes, in numerous cell types. Cohen, P. et al., 'Okadaic acid: a new probe for the study of cellular regulation.' Trends Biochem. Sci. 15: 98-102 (1990). Non-phorbol type tumor promoter. Suganuma, M. et al., 'Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.' Proc. Natl. Acad. Sci. USA 85: 1768-1771 (1988).