KN-92 (hydrochloride)

KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93 (Cay-13319).Formal Name: 2-[N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, monohydrochloride. CAS Number: 1431698-47-3. Molecular Formula: C24H25ClN2O3S . HCl. Formula Weight: 493.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml. lambdamax: 204, 251 nm. SMILES: CN(C/C=C/C1=CC=C(Cl)C=C1)CC2=CC=CC=C2N(S(=O)(C3=CC=C(OC)C=C3)=O)[H].O=P(OO)=O.[HH]. InChi Code: InChI=1S/C24H25ClN2O3S.ClH/c1-27(17-5-6-19-9-11-21(25)12-10-19)18-20-7-3-4-8-24(20)26-31(28,29)23-15-13-22(30-2)14-16-23,/h3-16,26H,17-18H2,1-2H3,1H/b6-5+,. InChi Key: SHDNWBMPAAXAHM-IPZCTEOASA-N.