Histone H3K79Me1 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt)

Histone H3K79Me1 (69-89) amide is a peptide fragment of histone H3 that corresponds to amino acid residues 70-90 of the human histone H3.1 and H3.2 sequences. Methylation of lysine 79 on histone H3 is associated with active chromatin and the silencing of telomere-associated genes by silent information regulator (Sir) proteins. The conversion of H3K79Me1 to H3K79Me2/3 is associated with increased expression of mixed lineage leukemia (MLL) target genes, including Hoxa9.Formal Name: L-arginyl-L-leucyl-L-valyl-L-arginyl-L-glutamyl-L-isoleucyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-N6-methyl-L-lysyl-L-threonyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-seryl-L-alanyl-L-valinamide, trifluoroacetate salt. Synonyms: Histone H3 (69-89) (Lys79me1) amide, [Lys(Me1)79]-Histone H3 (69-89) amide, RLVREIAQDF-K(Me1)-TDLRFQSSAV-NH2. Molecular Formula: C110H182N34O32 . XCF3COOH. Formula Weight: 2492.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Formic Acid: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.NC([C@H](C(C)C)NC([C@@H](NC([C@H](CO)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCCNC)NC([C@@H](NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@]([C@H](CC)C)([H])NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)N[H])=O)=O)=O)=O)=O)=O)C)=O)=O)CC(O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC(O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)C)=O)=O. InChi Code: InChI=1S/C110H182N34O32.C2HF3O2/c1-15-57(10)85(143-96(165)69(37-40-80(150)151)130-91(160)66(34-26-44-124-110(119)120)132-105(174)84(56(8)9)142-102(171)71(46-54(4)5)133-90(159)63(111)31-24-42-122-108(115)116)106(175)126-58(11)88(157)127-67(35-38-78(112)148)93(162)137-74(49-81(152)153)100(169)136-73(48-62-29-20-17-21-30-62)98(167)128-64(32-22-23-41-121-14)95(164)144-86(60(13)147)107(176)138-75(50-82(154)155)101(170)134-70(45-53(2)3)97(166)129-65(33-25-43-123-109(117)118)92(161)135-72(47-61-27-18-16-19-28-61)99(168)131-68(36-39-79(113)149)94(163)139-77(52-146)104(173)140-76(51-145)103(172)125-59(12)89(158)141-83(55(6)7)87(114)156,3-2(4,5)1(6)7/h16-21,27-30,53-60,63-77,83-86,121,145-147H,15,22-26,31-52,111H2,1-14H3,(H2,112,148)(H2,113,149)(H2,114,156)(H,125,172)(H,126,175)(H,127,157)(H,128,167)(H,129,166)(H,130,160)(H,131,168)(H,132,174)(H,133,159)(H,134,170)(H,135,161)(H,136,169)(H,137,162)(H,138,176)(H,139,163)(H,140,173)(H,141,158)(H,142,171)(H,143,165)(H,144,164)(H,150,151)(H,152,153)(H,154,155)(H4,115,116,122)(H4,117,118,123)(H4,119,120,124),(H,6,7)/t57-,58-,59-,60+,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,83-,84-,85-,86-,/m0./s1. InChi Key: QLZNMMZROFSSJL-OTTVTYNCSA-N.