Histone H3K14Ac/K18Ac/K23Ac/K27Ac (1-30)-GGK-biotin (trifluoroacetate salt)

Histone H3K14Ac/K18Ac/K23Ac/K27Ac (1-30)-GGK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 2-31 of the human histone H3 sequence. It is acetylated at lysine 14, lysine 18, lysine 23, and lysine 27 and biotinylated via a C-terminal GGK linker. Acetylation of H3K14, H3K18, H3K23, or H3K27 is associated with transcriptional activation, and H3K14 acetylation is required for trimethylation of H3K4.Synonyms: ARTKQTARKSTGG-K(Ac)-APR-K(Ac)-QLAT-K(Ac)-AAR-K(Ac)-SAPGG-K(biotin), Histone H3 (1-30) (Lys14ac/Lys18ac/Lys23ac/Lys27ac), [Lys(Ac)14/18/23/27]-Histone H3 (1-30)-GGK(biotin). Molecular Formula: C161H282N56O48S . XCF3COOH. Formula Weight: 3802.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: CC(NCCCC[C@@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCNC(C)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCNC(C)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCNC(C)=O)C(N[C@@H](CO)C(N[C@H](C(N2CCC[C@H]2C(NCC(NCC(N[C@@H](CCCCNC(CCCC[C@@H]3SC[C@@](N4)([H])[C@]3([H])NC4=O)=O)C(O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)C)=O)C)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)C)=O)NC(CNC(CNC([C@@]([C@@H](C)O)([H])NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCNC(N)=N)NC([C@@H](N[H])C)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C161H282N56O48S.C2HF3O2/c1-80(2)72-109(145(252)190-85(7)132(239)211-125(90(12)222)152(259)205-97(43-23-30-62-176-93(15)225)134(241)189-82(4)129(236)188-83(5)130(237)197-102(47-34-66-180-157(167)168)138(245)201-100(45-25-32-64-178-95(17)227)141(248)208-110(77-218)146(253)193-87(9)154(261)216-70-38-51-113(216)148(255)186-73-119(231)185-76-122(234)195-108(156(263)264)46-26-33-65-179-118(230)54-19-18-53-115-127-112(79-266-115)210-161(265)215-127)207-142(249)106(55-57-116(165)228)202-135(242)99(44-24-31-63-177-94(16)226)200-139(246)104(49-36-68-182-159(171)172)204-149(256)114-52-39-71-217(114)155(262)86(8)192-133(240)96(42-22-29-61-175-92(14)224)194-121(233)75-184-120(232)74-187-150(257)123(88(10)220)212-147(254)111(78-219)209-140(247)98(40-20-27-59-162)199-137(244)103(48-35-67-181-158(169)170)198-131(238)84(6)191-151(258)124(89(11)221)213-144(251)107(56-58-117(166)229)203-136(243)101(41-21-28-60-163)206-153(260)126(91(13)223)214-143(250)105(196-128(235)81(3)164)50-37-69-183-160(173)174,3-2(4,5)1(6)7/h80-91,96-115,123-127,218-223H,18-79,162-164H2,1-17H3,(H2,165,228)(H2,166,229)(H,175,224)(H,176,225)(H,177,226)(H,178,227)(H,179,230)(H,184,232)(H,185,231)(H,186,255)(H,187,257)(H,188,236)(H,189,241)(H,190,252)(H,191,258)(H,192,240)(H,193,253)(H,194,233)(H,195,234)(H,196,235)(H,197,237)(H,198,238)(H,199,244)(H,200,246)(H,201,245)(H,202,242)(H,203,243)(H,204,256)(H,205,259)(H,206,260)(H,207,249)(H,208,248)(H,209,247)(H,211,239)(H,212,254)(H,213,251)(H,214,250)(H,263,264)(H4,167,168,180)(H4,169,170,181)(H4,171,172,182)(H4,173,174,183)(H2,210,215,265),(H,6,7)/t81-,82-,83-,84-,85-,86-,87-,88+,89+,90+,91+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,123-,124-,125-,126-,127-,/m0./s1. InChi Key: NSLUQXYZNSRELK-RFNOJIOGSA-N.