HEMADO

HEMADO is a selective agonist of the adenosine A3 receptor (Kis = 1.1, 327, and 1,230 nM for A3, A1, and A2A receptors, respectively). HEMADO reduces release of lactate dehydrogenase (LDH) and creatine kinase-MB (CK-MB) from myocardium in isolated rat hearts subjected to ischemia-reperfusion injury.Formal Name: 2-(1-hexyn-1-yl)-N-methyl-adenosine. CAS Number: 403842-38-6. Molecular Formula: C17H23N5O4. Formula Weight: 361.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 236, 274, 298 nm. SMILES: O[C@H]1[C@@H](O)[C@H](N2C=NC3=C(NC)N=C(C#CCCCC)N=C32)O[C@@H]1CO. InChi Code: InChI=1S/C17H23N5O4/c1-3-4-5-6-7-11-20-15(18-2)12-16(21-11)22(9-19-12)17-14(25)13(24)10(8-23)26-17/h9-10,13-14,17,23-25H,3-5,8H2,1-2H3,(H,18,20,21)/t10-,13-,14-,17-/m1/s1. InChi Key: KOCIMZNSNPOGOP-IWCJZZDYSA-N.