GS-441524 (Remdesivir Metabolite)

GS-441524 (Remdesivir Metabolite)
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COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Rabatt Preis
AG-CR1-3722-M005 5 mg -

3 - 9 Werktage*

10 %
55,00 €
49,50 €
AG-CR1-3722-M010 10 mg -

3 - 9 Werktage*

10 %
88,00 €
79,20 €
AG-CR1-3722-M050 50 mg -

3 - 9 Werktage*

10 %
231,00 €
207,90 €
 
Soluble in DMSO (10mg/ml) or DMF (10mg/ml). GS-441524 is the active metabolite of the... mehr
Produktinformationen "GS-441524 (Remdesivir Metabolite)"
Soluble in DMSO (10mg/ml) or DMF (10mg/ml). GS-441524 is the active metabolite of the broad-spectrum antiviral Remdesivir. GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of viral RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production (RNA synthesis arrest), either by terminating RNA chains or causing mutations. It inhibits MERS-CoV or SARS-CoV-infected HAE cultures (EC50=74nM and 69nM) and murine hepatitis virus (MHV) (EC50=30nM). In vivo, remdesivir (Prod. No. AG-CR1-3713) (25 and 50 mg/kg) reduces lung viral titers and prevents weight loss in a mouse model of SARS-CoV infection. Remdesivir (Prod. No. AG-CR1-3713) is used as a treatment for Ebola virus disease and Marburg virus infections and other single stranded RNA viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, Nipah virus, Hendra virus and the coronaviruses (including MERS and SARS viruses). Remdesivir is effective in the control of 2019-nCoV (COVID-19) infection in vitro. It now also has been studied as potential treatment of SARS-CoV-2 infections.
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-CR1-3722

Eigenschaften

Anwendung: Antiviral nucleoside analog, active remdesivir metabolite
MW: 291.3 D
Formel: C12H13N5O4
Reinheit: >=98%
Format: Solid

Datenbank Information

CAS : 1191237-69-0| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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COVID-19 Forschung
GS-441524 GS-441524
ab 35,00 €
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