Daunorubicin, Hydrochloride Salt

Daunorubicin, Hydrochloride Salt
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
LC-D-6660_10mg 10 mg -

3 - 15 Werktage*

72,00 €
LC-D-6660_25mg 25 mg -

3 - 15 Werktage*

86,00 €
LC-D-6660_50mg 50 mg -

3 - 15 Werktage*

108,00 €
LC-D-6660_100mg 100 mg -

3 - 15 Werktage*

132,00 €
LC-D-6660_200mg 200 mg -

3 - 15 Werktage*

205,00 €
LC-D-6660_500mg 500 mg -

3 - 15 Werktage*

344,00 €
LC-D-6660_1g 1 g -

3 - 15 Werktage*

545,00 €
LC-D-6660_2g 2 g -

3 - 15 Werktage*

818,00 €
LC-D-6660_5g 5 g -

3 - 15 Werktage*

1.367,00 €
 
Soluble in DMSO. Daunorubicin, also known as daunomycin, is an anthracycline antibiotic that is... mehr
Produktinformationen "Daunorubicin, Hydrochloride Salt"
Soluble in DMSO. Daunorubicin, also known as daunomycin, is an anthracycline antibiotic that is one of the major antitumor agents widely used in the treatment of acute myeloid leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and Kaposi's sarcoma. Daunomycin and Actinomycin reduced mitotic activity and thymidine incorporation, whereas both processes appeared less affected by N-acetyldaunomycin. All three antibiotics inhibited nucleolar RNA synthesis at low doses. Di Marco A., et al. 'Inhibiting effect of the new cytotoxic antibiotic daunomycin on nucleic acids and mitotic activity of HeLa cells.' J. Cell Biol. 27: 545-550 (1965). Cytotoxicity mediated by daunorubicin is the result of drug-induced damage to DNA. Cell responses to daunorubicin are regulated by multiple signaling events, including a sphingomyelinase-initiated sphingomyelin-ceramide pathway, mitogen-activated kinase and stress-activated protein/c-Jun N-terminal kinase activation, transcription factors such as nuclear factor kappa B, and the Fas/Fas-ligand system. Laurent G. and Jaffrezou J.P. 'Signaling pathways activated by daunorubicin.' Blood 98: 913-924 (2001).
Schlagworte: Cerubidine, Daunoblastin, NDC 0082-4155, Ondena, RP 13057, Rubidomycin
Hersteller: LC Laboratories
Hersteller-Nr: D-6660

Eigenschaften

Anwendung: Antineoplastic, Topoisomerase II inhibitor
MW: 563.98 D
Formel: C27H29NO10.HCl
Reinheit: >98%
Format: Solid

Datenbank Information

CAS : 23541-50-6| Finde Alternativen
KEGG ID : K03164 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302+312+332
P-Sätze: P262
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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