10-deacetyl-7-xylosyl Paclitaxel

10-deacetyl-7-xylosyl Paclitaxel
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay32955-5 5 mg -

6 - 10 Werktage*

77,00 €
Cay32955-10 10 mg -

6 - 10 Werktage*

127,00 €
Cay32955-25 25 mg -

6 - 10 Werktage*

259,00 €
 
10-deactyl-7-xylosyl Paclitaxel is a disruptor of microtubules and derivative of paclitaxel... mehr
Produktinformationen "10-deacetyl-7-xylosyl Paclitaxel"
10-deactyl-7-xylosyl Paclitaxel is a disruptor of microtubules and derivative of paclitaxel (Cay-10461) that has been found in T. chinensis. It induces the disassembly of pig brain and Physarum microtubules in cell-free assays (IC50s = 0.3 and 0.5 µM, respectively). 10-deactyl-7-xylosyl Paclitaxel inhibits proliferation of (IC50 = 5 µM), as well as induces cell cycle arrest at the G2/M phase and apoptosis in, PC3 prostate cancer cells.Formal Name: (alphaR,betaS)-beta-(benzoylamino)-alpha-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(beta-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester. CAS Number: 90332-63-1. Molecular Formula: C50H57NO17. Formula Weight: 944.0. Purity: >60%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly, sonicated. SMILES: C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@H](C3=CC=CC=C3)NC(C4=CC=CC=C4)=O)=O)C[C@]5(O)C2(C)C)O)=O)[C@@]([C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]([C@@]7([H])C[C@@H]1O[C@@](OC[C@H]8O)([H])[C@@H]([C@H]8O)O)(CO7)OC(C)=O. InChi Code: InChI=1S/C50H57NO17/c1-25-31(65-45(61)38(56)35(27-15-9-6-10-16-27)51-43(59)28-17-11-7-12-18-28)22-50(62)42(67-44(60)29-19-13-8-14-20-29)40-48(5,41(58)37(55)34(25)47(50,3)4)32(21-33-49(40,24-64-33)68-26(2)52)66-46-39(57)36(54)30(53)23-63-46/h6-20,30-33,35-40,42,46,53-57,62H,21-24H2,1-5H3,(H,51,59)/t30-,31+,32+,33-,35+,36+,37-,38-,39-,40+,42+,46+,48-,49+,50-/m1/s1. InChi Key: ORKLEZFXASNLFJ-DYLQFHMVSA-N. Origin: Synthetic.
Schlagworte: (alphaR,betaS)-beta-(benzoylamino)-alpha-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(beta-D-xylopyranosylox
Hersteller: Cayman Chemical
Hersteller-Nr: 32955

Eigenschaften

Anwendung: Microtubule disruptor
MW: 944 D
Formel: C50H57NO17
Reinheit: >60%
Format: Solid

Datenbank Information

CAS : 90332-63-1| Passende Produkte
KEGG ID : K07374 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H315, H317, H318, H335, H361
P-Sätze: P201, P202, P261, P264, P271, P272, P280, P302+352, P304+340, P305+351+338, P308+313, P310, P312, P321, P332+313, P333+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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