Mitomycin C

Mitomycin C
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay11435-5 5 mg -

6 - 10 Werktage*

84,00 €
Cay11435-10 10 mg -

6 - 10 Werktage*

123,00 €
Cay11435-25 25 mg -

6 - 10 Werktage*

283,00 €
Cay11435-50 50 mg -

6 - 10 Werktage*

432,00 €
 
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S.... mehr
Produktinformationen "Mitomycin C"
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S. caespitosus. As an alkylating agent, its activity depends on reductive activation either through low pH or DT-diaphorase or NADH cytochrome c reductase. Activated MMC crosslinks double stranded DNA and is widely used as a tool to selectively inhibit DNA synthesis and mutagenensis, to stimulate genetic recombination, chromosome breakage and sister chromatid exchange, and to induce DNA repair. MMC has clinical significance in combination cancer chemotherapy of solid tumors as well as for modulating wound healing after ophthalmological surgeries and in the management of various corneal disorders.Formal Name: 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1aS,2,8S,8aR,8bS-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. CAS Number: 50-07-7. Synonyms: Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980. Molecular Formula: C15H18N4O5. Formula Weight: 334.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 0.1 mg/ml, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 216, 359 nm. SMILES: NC1=C(C)C(C(N(C[C@H]2[C@@H]3N2)[C@@]3(OC)[C@@H]4COC(N)=O)=C4C1=O)=O. InChi Code: InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1. InChi Key: NWIBSHFKIJFRCO-WUDYKRTCSA-N.
Schlagworte: Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1aS,2,8S,8aR,8bS-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Hersteller: Cayman Chemical
Hersteller-Nr: 11435

Eigenschaften

Anwendung: Antitumor antibiotic
MW: 334.3 D
Formel: C15H18N4O5
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 50-07-7| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H300, H310, H330, H351
P-Sätze: P201, P202, P260, P262, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P308+313, P310, P320, P321, P330, P361+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Mitomycin C"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen