Aztreonam-d6

Aztreonam-d6
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay28799-500 500 µg -

6 - 10 Werktage*

488,00 €
 
Aztreonam-d6 is intended for use as an internal standard for the quantification of aztreonam... mehr
Produktinformationen "Aztreonam-d6"
Aztreonam-d6 is intended for use as an internal standard for the quantification of aztreonam (Cay-19784) by GC- or LC-MS. Aztreonam is a synthetic beta-lactam antibiotic of the monobactam class. It is active against clinical isolates of E. coli, S. marcescens, P. aeruginosa, Klebsiella species, Proteus species, and Enterobacter species (MICs = S. pneumoniae, B. fragilis, and S. faecalis (MICs = >100 µg/ml for all). It interferes with peptidoglycan synthesis in the bacterial cell wall of the Gram-negative bacteria E. coli, P. vulgaris, E. cloacae, K. pneumoniae, and P. aeruginosa by inhibiting penicillin-binding protein 3 (PBP3, IC100 = 0.1 µg/ml for all). It increases survival in mice with systemic Gram-negative bacterial infections (ED50s = 0.1-24.7 mg/kg). Formulations containing aztreonam have been used in the treatment of P. aeruginosa infections in individuals with cystic fibrosis.Formal Name: 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-(methyl-d3)-propanoic-3,3,3-d3 acid. CAS Number: 1127452-94-1. Synonyms: SQ 26,776-d6. Molecular Formula: C13H11D6N5O8S2. Formula Weight: 441.5. Purity: >99% deuterated forms (d1-d6). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: OS(N([C@@H](C)[C@@H]1NC(/C(C2=CSC(N)=N2)=N\OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(O)=O)=O)C1=O)(=O)=O. InChi Code: InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1/i2D3,3D3. InChi Key: WZPBZJONDBGPKJ-XFXAWXATSA-N.
Schlagworte: SQ 26,776-d6, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-(methyl-d3)-propanoic-3,3,3-d3 acid
Hersteller: Cayman Chemical
Hersteller-Nr: 28799

Eigenschaften

Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Antibiotic
MW: 441.5 D
Formel: C13H11D6N5O8S2
Reinheit: >99% deuterated forms (d1-d6)
Format: Solid

Datenbank Information

CAS : 1127452-94-1| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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