WM88 Viable Cells

WM88 Viable Cells
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
WM88-01-0001 1 ml (1.0 million cells/ml) - -

6 - 10 Werktage*

1.568,00 €
WM88-01-0005 1 ml (5 x 10^6 cells) - -

6 - 10 Werktage*

5.226,00 €
WM88-01-0010 1 ml (10 x 10^6 cells) - -

6 - 10 Werktage*

7.841,00 €
 
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for... mehr
Produktinformationen "WM88 Viable Cells"
Cells are sterile, validated by short tandem repeat profiling, and are tested as negative for mycoplasma. It is recommended that cell lines are tested for mycoplasma contamination and short tandem repeat (STR) profiling every 10 passages or each time a frozen seed stock is made. See cell culture protocol for additional details. WM88 is a tumorigenic primary melanoma cell line with competence for metastasis. These cells display melanocytic morphology in culture. This cell line was established from a metastatic site in a male patient with level III superficial spreading melanoma with tumor thickness of 0.92. This cell line contains the V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation occurs within the activation segment of the kinase domain and causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. The cells are wild type for PTEN, N-ras, c-KIT and CDK4. WM88 cells produce xenograft tumors when injected into immunocompromised mice.
Hersteller: Rockland Immunochemicals
Hersteller-Nr: WM88-01-0010

Eigenschaften

Anwendung: Genetic studies, xenograft production, drug testing, drug target discovery
Wirt: Human
Spezies-Reaktivität: human
Format: Frozen Cell Suspension

Datenbank Information

Handhabung & Sicherheit

Lagerung: Liquid nitrogen
Versand: -80°C (International: -80°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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