PXR (human) Reporter Assay Kit

PXR (human) Reporter Assay Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IB-IB07001 96 wells - -

5 - 17 Werktage

1.121,00 €
IB-IB07001-32 96 wells (3x32 wells) - -

5 - 17 Werktage

1.188,00 €
 
Protein function: Nuclear receptor that binds and is activated by variety of endogenous and... mehr
Produktinformationen "PXR (human) Reporter Assay Kit"
Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. [The UniProt Consortium]
Schlagworte: SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic receptor, Nuclear receptor subfamily 1 group I member 2
Hersteller: Indigo Biosciences
Hersteller-Nr: IB07001

Eigenschaften

Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -80°C (International: -80°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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