LXR (human) Reporter Assays Panel

LXR (human) Reporter Assays Panel
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IB-IB00321-48P 96 wells - -

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1.422,00 €
INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human... mehr
Produktinformationen "LXR (human) Reporter Assays Panel"
INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (NR1H3) and beta (NR1H2), ligand-dependent transcription factors commonly referred to as LXRalpha and LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an LXR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in LXR activity. The principal application of this reporter assay system is in the screening of test samples to quantify any functional activity, either agonist or antagonist, that they may exert against the human LXRs. LXR reporter cells are prepared using INDIGO's proprietary CryoMite(TM) process. This cryo-preservation method yields exceptional cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for cumbersome intermediate treatment steps such as spin-and-rinse of cells, viability determinations, cell titer adjustments, or the pre-incubation of reporter cells prior to assay setup. INDIGO Bioscience's nuclear receptor reporter assays are all-inclusive cell-based assay systems. In addition to LXR reporter cells, this kit provides two optimized media for use during cell culture and in diluting the user's test samples, a reference agonist, luciferase detection reagent, and a cell culture-ready assay plate.
Hersteller: Indigo Biosciences
Hersteller-Nr: IB00321-48P


Anwendung: Functional activity screening
Reaktivität: Human
Format: Solid Phase

Datenbank Information

KEGG ID : K08535 | Suche mit KEGG ID

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -80°C (International: -80°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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