NIR-FLIVO(TM) 747 in vivo Apoptosis Kit (DyLight(R) 747-VAD-FMK), 20 tests

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ICT-9114 20 tests -

3 - 10 Werktage*

629,00 €
 
NIR-FLIVO(TM) in vivo Apoptosis Kits provide an accurate and direct method to image apoptosis in... mehr
Produktinformationen "NIR-FLIVO(TM) 747 in vivo Apoptosis Kit (DyLight(R) 747-VAD-FMK), 20 tests"
NIR-FLIVO(TM) in vivo Apoptosis Kits provide an accurate and direct method to image apoptosis in vivo. With its ability to be imaged noninvasively, NIR-FLIVO(TM) 747 is a powerful imaging tool, allowing longitudinal studies and eliminating false positives that may arise from ex vivo manipulation of tissue. All FLIVO(TM) (FLuorescence in vIVO) tracers are non-cytotoxic fluorescent inhibitors of the class of cysteine proteases known as caspases, which are associated with the execution of apoptosis. After intravenous injection, the FLIVO(TM) tracers circulate throughout the body and preferentially form covalent bonds with active caspases, marking apoptotic cells with its fluorescent signal. The bound FLIVO(TM) tracer will remain inside the cell as long as the cell membrane is intact. Any unbound FLIVO(TM) is removed with the natural circulation of the animal. The resulting fluorescent signal within samples is a direct measure of apoptosis that was occurring at the time the reagent was injected. FLIVO(TM) is non-toxic, cell-permeant, and crosses the blood-brain barrier. Reagent titration experiments should be performed to determine the amount of reagent that will work best for the size of the animal and the target tissue type. Apoptosis detection with FLIVO(TM) provides a true representation of the induction of apoptosis as a result of the experimental condition. Applications: FLIVO(TM) may be used in animal models to monitor the efficacy of treatment or the effects of disease.
Schlagworte: Fluorescent inhibitor, Apoptosis tracer
Hersteller: ImmunoChemistry Technologies
Hersteller-Nr: 9114

Eigenschaften

Anwendung: In vivo apoptosis detection
Format: Homog.

Datenbank Information

Handhabung & Sicherheit

Lagerung: vT
Versand: vT (International: °C)
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