TRAIL R1 (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 31.25-1000 pg/ml, Sensitivity: 8 pg/ml, Cross reaction: No cross reactivity observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178 and Granzyme B., Incubation time: 2h30, Sample Types: Serum, Cell lysates, Cell culture supernatant, Sample Size: 100 µl Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed:19090789). Promotes the activation of NF- kappa-B (PubMed:9430227). [The UniProt Consortium]