Mouse IL-23 (Interleukin 23) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of IL-23 in serum, plasma and other biological fluids. Detection Range: 15.63--1000pg/mL. Sensitivity: 9.38pg/mL. Protein function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. [The UniProt Consortium]