Human soluble CD6 ELISA Kit

Human soluble CD6 ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
KOA0714 1 kit - -

6 - 10 Werktage*

848,00 €
 
Natural and recombinant human CD6. There is no detectable cross-reactivity with other relevant... mehr
Produktinformationen "Human soluble CD6 ELISA Kit"
Natural and recombinant human CD6. There is no detectable cross-reactivity with other relevant proteins. Protein function: Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24945728, PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule, promotes T-cell activation and proliferation (PubMed:15294938, PubMed:16352806, PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938, PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777). [The UniProt Consortium]
Schlagworte: CD6
Hersteller: Rockland Immunochemicals
Hersteller-Nr: KOA0714

Eigenschaften

Anwendung: ELISA
Wirt: Human
Spezies-Reaktivität: human
Immunogen: Expression system for standard: NSO, Immunogen sequence: H18-E398
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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