Human sCD163 (Soluable Cluster of Differentiation 163) ELISA Kit

Human sCD163 (Soluable Cluster of Differentiation 163) ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-EL-H0036.96 96 wells -

7 - 16 Werktage*

483,00 €
 
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of sCD163 in... mehr
Produktinformationen "Human sCD163 (Soluable Cluster of Differentiation 163) ELISA Kit"
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of sCD163 in serum, plasma and other biological fluids. Detection Range: 1.56--100ng/mL. Sensitivity: 0.94ng/mL. Protein function: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. [The UniProt Consortium]
Schlagworte: M130, CD163
Hersteller: Elabscience
Hersteller-Nr: E-EL-H0036

Eigenschaften

Anwendung: ELISA
Spezies-Reaktivität: human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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