Human PTHrP (Parathyroid Hormone Related Protein) ELISA Kit

Human PTHrP (Parathyroid Hormone Related Protein) ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-EL-H1478.96 96 wells - -

7 - 16 Werktage*

554,00 €
 
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of PTHrP in serum,... mehr
Produktinformationen "Human PTHrP (Parathyroid Hormone Related Protein) ELISA Kit"
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of PTHrP in serum, plasma and other biological fluids. Detection Range: 15.63--1000pg/mL. Sensitivity: 9.38pg/mL. Protein function: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath. Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1- dependent manner through activation of Rac1. [The UniProt Consortium]
Schlagworte: PTHLH, PTHRP
Hersteller: Elabscience
Hersteller-Nr: E-EL-H1478

Eigenschaften

Anwendung: ELISA
Reaktivität: Human
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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