Human IL-17C ELISA Kit

Human IL-17C ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
KOA0465 1 kit - -

6 - 10 Werktage*

1.136,00 €
 
Natural and recombinant human IL-17C. There is no detectable cross-reactivity with other relevant... mehr
Produktinformationen "Human IL-17C ELISA Kit"
Natural and recombinant human IL-17C. There is no detectable cross-reactivity with other relevant proteins. Protein function: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. [The UniProt Consortium]
Schlagworte: IL17C, IL-17C, Cytokine CX2, Interleukin-17C
Hersteller: Rockland Immunochemicals
Hersteller-Nr: KOA0465

Eigenschaften

Anwendung: ELISA
Wirt: Human
Spezies-Reaktivität: human
Immunogen: Expression system for standard: E.colI, Immunogen sequence: H19-V197
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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