Human GzmB (Granzyme B) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of GzmB in serum, plasma and other biological fluids. Detection Range: 15.63--1000pg/mL. Sensitivity: 9.38pg/mL. Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [The UniProt Consortium]