DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit

DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay589320-96S 96 so-wells (96 solid wells) -

6 - 10 Werktage*

769,00 €
Cay589320-96 96 st-wells (96 strip wells) -

6 - 10 Werktage*

769,00 €
Cay589320-480 480 st-wells (480 strip wells) -

6 - 10 Werktage*

2.876,00 €
Cay589320-480S 480 so-wells (480 solid wells) -

6 - 10 Werktage*

2.876,00 €
 
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including... mehr
Produktinformationen "DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit"
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2'-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman's DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.Synonyms: DNA/RNA Oxidative Damage (High Sensitivity) EIA Kit, 8-hydroxy-2'-Deoxyguanosine, 8-OH-DG, 8-OH-2dG. Assay Range: 10.3-3,000 pg/ml. Sensitivity: 80% B/B0: 30 pg/ml. Mid-point: 50% B/B0: 90-140 pg/ml. Cross Reactivity: (8-hydroxy-2'-deoxyguanosine) 100%, (8-hydroxyguanosine) 38%, (8-hydroxyguanine) 23%, (Guanosine) <0.01%. Origin: Animal/Goat, Animal/Bovine, Animal/Eel, Animal/Mouse.
Schlagworte: 8-hydroxy-2'-Deoxyguanosine, 8-OH-2dG, 8-OH-DG, DNA/RNA Oxidative Damage (High Sensitivity) EIA Kit
Hersteller: Cayman Chemical
Hersteller-Nr: 589320

Eigenschaften

Anwendung: ELISA
Format: Solid Phase

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H301, H302, H311, H315, H318, H319, H335, H350, H373
P-Sätze: P201, P202, P210, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P312, P314, P321, P330, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P332+P313, P337+P313, P361+P364, P362+P364, P370+P378, P405, P403+P233, P403+P235, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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