Corticosterone ELISA Kit

Corticosterone is a glucocorticoid produced by the adrenal cortex in response to ACTH (corticotropic hormone) and is the precursor to aldosterone. The production of glucorcorticoids is increased by stress, therefore, corticosterone can be used as a biomarker of stress. Biologists often measure corticosterone in fecal material of the species they are studying. This non-invasive sample collection procedure has the advantage of not itself causing stress and thereby increasing corticosterone levels, a common problem when samples for measurement of corticosterone are collected by more invasive means. Plasma corticosterone levels have a circadian variation and corticosterone may be important in the regulation of the sleep-wake cycle. Cayman's Corticosterone ELISA Kit is a competitive assay that can be used for quantification of corticosterone in serum and rodent feces.Synonyms: Corticosterone EIA Kit, 17-deoxy Cortisol, 11beta,21-DHP, 11beta,21-dihydroxy Progesterone. Assay Range: 8.2-5,000 pg/ml. Sensitivity: 80% B/B0: 30 pg/ml. Mid-point: 50% B/B0: 130-180 pg/ml. Cross Reactivity: (Corticosterone) 100%, (11-Deoxycorticosterone) 15.8%, (Prednisolone) 3.4%, (11-Dehydrocorticostone) 2.9%, (Cortisol) 2.5%, (Progesterone) 1.4%, (Aldosterone) 0.47%, (17alpha-Hydroxyprogesterone) 0.21%, (11-Deoxycortisol) 0.14%, (Androstenedione) 0.11%, (Testosterone) 0.07%, (Pregnenolone) 0.03%, (DHEA sulfate) 0.0005%, (Androstenediol) <0.01%, (Dexamethasone) <0.01%, (DHEA) <0.01%, (5alpha-DHT) <0.01%, (Estradiol) <0.01%, (Estriol) <0.01%, (Estrone sulfate) <0.01%, (Ethynylestradiol) <0.01%, (17alpha-Hydroxypregnenolone) <0.01%. Origin: Animal/Rabbit, Animal/Bovine, Animal/Eel.