Canakinumab (Ilaris(R))-Antibody screening - Qualitative

Canakinumab (Ilaris(R))-Antibody screening - Qualitative
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-HUMB00057.96 96 assays - -

9 - 20 Werktage*

1.122,00 €
 
ELISA Genie Qualitative Antibodies to Canakinumab ELISA has been especially developed for the... mehr
Produktinformationen "Canakinumab (Ilaris(R))-Antibody screening - Qualitative"
ELISA Genie Qualitative Antibodies to Canakinumab ELISA has been especially developed for the qualitative analysis of antibodies to canakinumab in serum and plasma samples. ELISA Genie Qualitative Antibodies to Canakinumab ELISA is optimized with Ilaris(R)Canakinumab (Ilaris(R)) Antibody screening - Qualitative ELISA Kit test principle Solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle. Controls and samples (serum or plasma) are incubated in the microtiter plate coated with the drug canakinumab. After incubation, the wells are washed. Then, horse radish peroxidase (HRP) conjugated probe is added and binds to canakinumab antibodies captured by the drug canakinumab on the surface of the wells. Following incubation wells are washed and the bound enzymatic activity is detected by addition of chromogen-substrate. Finally, the reaction is terminated with an acidic stop solution. The colour developed is proportional to the amount of canakinumab antibodies in the sample or controls. The results can be evaluated with using cutoff value. About Canakinumab (Ilaris(R)) Antibody screening - Qualitative ELISA Kit: Canakinumab is a recombinant, human anti-human-IL-1beta monoclonal antibody that belongs to the IgG1/kappa isotype subclass. Canakinumab binds to human IL-1beta and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).In inflammatory diseases involving Cryopyrin-Associated Periodic Syndromes (CAPS), interleukin-1 beta (IL-1beta) is excessively activated and drives inflammation. The protein cryopyrin controls the activation of IL-1beta, and mutations in cryopyrin's gene, NLRP-3, up-regulate IL-1beta activation. Canakinumab is a human monoclonal anti-human IL-1beta antibody of the IgG1/kappa isotype. Canakinumab binds to human IL-1beta and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).ELISA Genie ELISA kits can be used for drug level and anti-drug antibodies measurements.
Hersteller: Assay Genie
Hersteller-Nr: HUMB00057

Eigenschaften

Anwendung: Antibody screening - Qualitative
Format: Solid Phase

Datenbank Information

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Canakinumab (Ilaris(R))-Antibody screening - Qualitative"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen