Angiopoietin-Related Protein 3, BioAssay(TM) ELISA Kit (Mouse) (ANGPTL3, ANGPT5, Angiopoietin 5, Ang

Angiopoietin-Related Protein 3, BioAssay(TM) ELISA Kit (Mouse) (ANGPTL3, ANGPT5, Angiopoietin 5, Ang
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
227500.24 24 tests - -

1 - 19 Werktage

519,00 €
227500.48 48 tests - -

1 - 19 Werktage

602,00 €
227500.96 96 tests - -

1 - 19 Werktage

757,00 €
 
Protein function: Acts in part as an hepatokine that is involved in regulation of lipid and... mehr
Produktinformationen "Angiopoietin-Related Protein 3, BioAssay(TM) ELISA Kit (Mouse) (ANGPTL3, ANGPT5, Angiopoietin 5, Ang"
Protein function: Acts in part as an hepatokine that is involved in regulation of lipid and glucose metabolism (PubMed:11788823, PubMed:12671033). Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake (PubMed:26305978). Has a stimulatory effect on plasma triglycerides (TG), which is achieved by suppressing plasma TG clearance via inhibition of LPL activity, the function seems to be specific for the feeding conditions. The inhibition of LPL activity appears to be an indirect mechanism involving recruitment of proprotein convertases PCSK6 and FURIN to LPL leading to cleavage and dissociation of LPL from the cell surface, the function does not require ANGPTL3 proteolytic cleavage but seems to be mediated by the N-terminal domain, and is not inhibited by GPIHBP1 (PubMed:12909640, PubMed:16081640, PubMed:20581395). Can inhibit endothelial lipase, causing increased plasma levels of high density lipoprotein (HDL) cholesterol and phospholipi
Schlagworte: Angptl3
Hersteller: United States Biological
Hersteller-Nr: 227500

Eigenschaften

Anwendung: ELISA
Reaktivität: Mouse
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: vT
Versand: +4°C (International: vT)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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