SARS-CoV-2 Inhibitor Screening Kit

SARS-CoV-2 Inhibitor Screening Kit
COVID-19 Forschung
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
AG-48B-0001-KI01 96 wells

3 - 9 Werktage*

715,00 €
 
To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD)... mehr
Produktinformationen "SARS-CoV-2 Inhibitor Screening Kit"
To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells. The SARS-CoV-2 Inhibitor Screening Kit contains key reagents required to facilitate identification of SARS-CoV-2 inhibitors. This inhibitor screen is based on a colorimetric ELISA kit, which measures the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2. This assay allows to identify and characterize the effect of different inhibitory molecules including antibodies or chemicals on the prevention of binding of SARS-CoV-2 virus to any ACE2-expressing cells.
Schlagworte: COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor Screening Kit.
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-48B-0001

Eigenschaften

Anwendung: Compound Screening
Reaktivität: Human
Format: Solid Phase

Datenbank Information

KEGG ID : K09708 | Finde Alternativen
UniProt ID : Q9BYF1 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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