COX Fluorescent Inhibitor Screening Assay Kit

COX Fluorescent Inhibitor Screening Assay Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay700100-192 192 wells -

5 - 10 Werktage*

719,00 €
 
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme... mehr
Produktinformationen "COX Fluorescent Inhibitor Screening Assay Kit"
Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) is a bifunctional enzyme exhibiting both COX and peroxidase activities. The COX component converts arachidonic acid to a hydroperoxy endoperoxide (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol (PGH2), the precursor of PGs, thromboxanes, and prostacyclins. It is now well established that there are two distinct isoforms of COX, COX-1 and COX-2. Cayman's COX Fluorescent Inhibitor Screening Assay provides a convenient fluorescence-based method for screening ovine COX-1 and human recombinant COX-2 for isozyme-specific inhibitors. The assay utilizes the peroxidase component of COXs. In this assay, the reaction between PGG2 and ADHP (10-acetyl-3,7-dihydroxyphenoxazine) produces the highly fluorescent compound resorufin. Resorufin fluorescence can be analyzed with an excitation wavelength of 530-540 nm and an emission wavelength of 585-595 nm. Synonyms: Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit. Origin: Animal/Sheep.
Schlagworte: Cyclooxygenase Fluorescent Inhibitor Screening Assay Kit
Hersteller: Cayman Chemical
Hersteller-Nr: 700100

Eigenschaften

Anwendung: COX inhibitor screening

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -80°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H227, H301, H302, H315, H316, H317, H319
P-Sätze: P210, P233, P240, P241, P242, P243, P261, P264, P270, P272, P280, P301+310, P302+352, P303+361+353, P305+351+338, P321, P330, P332+313, P333+313, P337+313, P362+364, P370+378, P403, P403+235, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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