Anti-Polyglutamylation Modification, clone GT335

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
AG-20B-0020-C100 100 µg -

ca. 1-3 Werktage

418,00 €
 
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with... mehr
Produktinformationen "Anti-Polyglutamylation Modification, clone GT335"
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved from and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and involved in cell cycle and cell proliferation.
Schlagworte: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Hersteller: AdipoGen Life Sciences
Hersteller-Nr: AG-20B-0020

Eigenschaften

Anwendung: ICC, IP, WB
Antikörper-Typ: Monoclonal
Klon: GT335
Konjugat: No
Wirt: Mouse
Reaktivität: All
Immunogen: Octapeptide EGEGE*EEG, modified by the addition of two glutamyl units onto the fifth E (indicated by an asterik).
Format: Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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