Anti-phospho-Stat 5a (Ser726) (Signal Transducer And Activator Of Transcription 5A, STAT5A, STAT5) (

Anti-phospho-Stat 5a (Ser726) (Signal Transducer And Activator Of Transcription 5A, STAT5A, STAT5) (
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
S7972-10B-HRP.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
STAT5a is a member of the STAT family of transcription factors. In response to cytokines and... mehr
Produktinformationen "Anti-phospho-Stat 5a (Ser726) (Signal Transducer And Activator Of Transcription 5A, STAT5A, STAT5) ("
STAT5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this protein is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells. Applications: Suitable for use in ELISA, Western Blot, Dot Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-phospho-STAT5, Anti-phospho-STAT5A, Anti-phospho-Signal transducer and activator of transcription 5A
Hersteller: United States Biological
Hersteller-Nr: S7972-10B-HRP

Eigenschaften

Anwendung: ELISA, Dot Blot, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: HRP
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser726 of human STAT5a (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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