Anti-phospho-LC3B (Thr93) (MAP1LC3B, LC3B, MAP1A/1BLC3, MAP1LC3B)

Anti-phospho-LC3B (Thr93) (MAP1LC3B, LC3B, MAP1A/1BLC3, MAP1LC3B)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
037701.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions... mehr
Produktinformationen "Anti-phospho-LC3B (Thr93) (MAP1LC3B, LC3B, MAP1A/1BLC3, MAP1LC3B)"
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Applications: Suitable for use in Dot Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Dot Blot 1:500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-phospho-MAP1LC3B, Anti-phospho-MAP1ALC3, Anti-phospho-MAP1A/MAP1B LC3 B, Anti-phospho-MAP1A/MAP1B light chain 3 B, Anti-phospho-Autophagy-related protein LC3 B, Anti-phospho-MAP1 light chain 3-like protein 2
Hersteller: United States Biological
Hersteller-Nr: 037701

Eigenschaften

Anwendung: ELISA, Dot Blot
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Phospho-LC3B-T93 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 83~112 amino acids surrounding T93 of human MAP1LC3B.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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