Anti-phospho-FGFR1 (Tyr307) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncoge

Anti-phospho-FGFR1 (Tyr307) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncoge
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
F4305-08B.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid... mehr
Produktinformationen "Anti-phospho-FGFR1 (Tyr307) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncoge"
FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 , Dot Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: EC=2.7.10.1, Anti-phospho-N-sam, Anti-phospho-BFGFR, Anti-phospho-bFGF-R-1, Anti-phospho-Fms-like tyrosine kinase 2, Anti-phospho-Fibroblast growth factor receptor 1, Anti-phospho-Basic fibroblast growth factor receptor 1
Hersteller: United States Biological
Hersteller-Nr: F4305-08B

Eigenschaften

Anwendung: ELISA, Dot Blot, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Y307 of human FGFR1 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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