Anti-phospho-FAS (Tyr291) (Tumor Necrosis Factor Receptor Superfamily Member 6, FASLG Receptor, Apop

Anti-phospho-FAS (Tyr291) (Tumor Necrosis Factor Receptor Superfamily Member 6, FASLG Receptor, Apop
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
F0019-59-HRP.200 200 µl - -

1 - 19 Werktage

696,00 €
 
FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has... mehr
Produktinformationen "Anti-phospho-FAS (Tyr291) (Tumor Necrosis Factor Receptor Superfamily Member 6, FASLG Receptor, Apop"
FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 , Dot Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-phospho-FAS, Anti-phospho-CD95, Anti-phospho-APT1, Anti-phospho-Apo-1 antigen, Anti-phospho-FASLG receptor, Anti-phospho-Apoptosis-mediating surface antigen FAS, Anti-phospho-Tumor necrosis factor receptor superfamily member 6
Hersteller: United States Biological
Hersteller-Nr: F0019-59-HRP

Eigenschaften

Anwendung: ELISA, Dot Blot, WB
Antikörper-Typ: Polyclonal
Konjugat: HRP
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr291 of human FAS (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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