Anti-phospho-EphA7 (Tyr791)

Anti-phospho-EphA7 (Tyr791)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG66572.100 100 µg - -

6 - 14 Werktage*

584,00 €
 
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A... mehr
Produktinformationen "Anti-phospho-EphA7 (Tyr791)"
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. [The UniProt Consortium]
Schlagworte: Anti-phospho-EHK3, Anti-phospho-EK11, Anti-phospho-hEK11, Anti-phospho-EHK-3, Anti-phospho-EPHA7, EC=2.7.10.1, Anti-phospho-EPH-like kinase 11, Anti-phospho-EPH homology kinase 3, Anti-phospho-Ephrin type-A receptor 7
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG66572

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Phosphospecific peptide around Tyr791 of Human EphA7
MW: 112 kD
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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