Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi

Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E8949-40N-Biotin.200 200 µl - -

1 - 19 Werktage

696,00 €
 
eIF4F is a multi-subunit complex, the composition of which varies with external and internal... mehr
Produktinformationen "Anti-phospho-EIF4E (Ser209) (Eukaryotic Translation Initiation Factor 4E, eIF4E, eIF-4E, mRNA Cap-bi"
eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners. The interaction with EIF4ENIF1 mediates the import into the nucleus. Nonphosphorylated EIF4EBP1, EIF4EBP2 and EIF4EBP3 compete with EIF4G1/EIF4G3 to interact with EIF4E, insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. Rapamycin can attenuate insulin stimulation, mediated by FKBPs. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-phospho-eIF4E, Anti-phospho-EIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit, Anti-phospho-mRNA cap-binding protein, Anti-phospho-Eukaryotic translation initiation factor 4E
Hersteller: United States Biological
Hersteller-Nr: E8949-40N-Biotin

Eigenschaften

Anwendung: ELISA, Dot Blot
Antikörper-Typ: Polyclonal
Konjugat: Biotin
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser209 of human EIF4E (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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